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Annexa dating

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Portola is developing Andex Xa as a universal reversal agent for patients anticoagulated with an oral or injectable Factor Xa inhibitor who experience a serious uncontrolled or life-threatening bleeding event or who require urgent or emergency surgery.

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The BLA seeks initial approval of Andex Xa for reversal of the anticoagulant effects of apixaban and rivaroxaban in patients experiencing uncontrolled or life-threatening bleeding.

treated with oral Factor Xa inhibitors were subsequently admitted to the hospital due to bleeding.

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Andexanet alfa is also under review by the European Commission of the European Medicines Agency (EMA).