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Oral pretreatment with the methanolic extract of E.retusa (200 mg/kg) exhibited a significant inhibition of pain induced either by acetic acid or by the heating plate and in a manner comparable to the standard drug paracetamol. retusa significantly reduced paw edema starting from the 3rd hour after carrageenan administration by increasing the activity of antioxidant enzymes (SOD, CAT, and GPx) in liver and paw tissues and decreasing the levels of MDA.Therefore, inflammation must be well regulated in these early stages.Several studies have demonstrated that the main mechanisms involved in the inflammatory reaction are closely associated with the generation of free radicals and the creation of oxidative stress.Naturally derived colours from fruit, vegetables and clays. - Inside Heart Gardenia anti-aging, limits natural aging, revitalizes, helps to decrease cell disorganization, contributes to maintain cell balance, anti-oxidating, against free radicals - l-ascorbic acid (pure stabilized Vitamin C) is effective against wrinkles and fine lines - Gotu Kola extract is anti-aging and it strengthens and improves skin tone - Apple is extremely rich in polyphenols - Hyaluronic Acid moisturizes and rejuvenates - Brazilian Rare Clays offer natural and stable colours; reduce photo-aging and aging signs around the eyes - Essential Oil of Sweet Orange and Vanilla lend their seductive scents Normal/Dry Skin Ingredients: aqua (p H-balanced distilled water), carthamus tinctorius (safflower) seed oil, caprylic/capric triglyceride, butyrospermum parkii (shea) butter, glycerin (vegetable derived), aloe barbadensis (aloe vera) gel, centella asiatica (gotu kola) extract, montmorillonite (Brazilian rare clays), cetearyl olivate, sorbitan olivate, gardenia jasminoides, rubiaceae (inside heart gardenia), pyrus malus (apple) extract, lotus corniculatus flower extract, zinc oxide, caffeine, sodium PCA, l-ascorbic acid (vitamin C), xanthan gum, iron oxides, serecite, citrus sinensis (orange) oil, vanilla extract, lonicera caprifolium (honeysuckle) flower extract, sodium hyaluronate (hyaluronic acid).aqua (p H-balanced distilled water), glycerin (vegetable derived), aloe barbadensis (aloe vera) gel, montmorillonite (Brazilian rare clays), cetearyl olivate, sorbitan olivate, gardenia jasminoides, rubiaecae (inside heart gardenia), pyrus malus (apple) extract, lotus corniculatus flower extract, zinc oxide, caffeine, sodium PCA l-ascorbic acid (vitamin C), xanthan gum, iron oxides, serecite, citrus sinensis (orange) oil, vanilla extract, lonicera caprifolium (honeysuckle) flower extract, sodium hyaluronate (hyaluronic acid).With so many options introduced daily, finding the best anti-aging treatment can become overwhelming.Marta Wohrle, founder of Truth In Aging, and her community of real women (and men!

Euphorbia is the largest genus of the family Euphorbiaceae and comprises about 1000 species.The aim of this study is to investigate the phytochemical constituents of the methanolic extracts of Euphorbia retusa and to evaluate their antioxidant, anti-inflammatory, and analgesic activities.The phytochemical results obtained by HPLC and by chemical assay reactions have revealed the richness of the methanolic extract of E.For these reasons, the use of medicinal plants has become the new strategy of several studies to develop and introduce new drugs with greater safety and efficiency.Indeed, medicinal plants contain a large number of bioactive molecules of multiple interests not only in traditional medicine but also in the food and pharmaceutical industry.

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